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Trial details imported from ClinicalTrials.gov

For full trial details, please see the original record at https://clinicaltrials.gov/study/NCT02280551

Registration number

NCT02280551

Ethics application status

Date submitted

29/10/2014

Date registered

31/10/2014

Date last updated

6/05/2021

Titles & IDs

Public title

The Australian Parental Supply of Alcohol Longitudinal Study (APSALS)

Scientific title

The Australian Parental Supply of Alcohol Longitudinal Study (APSALS)

Secondary ID [1]

DP:1096668

Universal Trial Number (UTN)

Trial acronym

APSALS

Linked study record

Health condition

Health condition(s) or problem(s) studied:

Alcohol Abuse

Condition category

Condition code

Mental Health

Addiction

Intervention/exposure

Study type

Observational

Patient registry

Target follow-up duration

Target follow-up type

Description of intervention(s) / exposure

Adolescents - 1927 Grade 7 high school students

Parent - A parent of each of the 1927 Grade 7 high school students

Comparator / control treatment

Control group

Outcomes

Primary outcome [1]

Frequency of alcohol consumption

Timepoint [1]

12 month

Primary outcome [2]

Typical quantity of alcohol consumption

Timepoint [2]

12 month

Primary outcome [3]

Frequency of binge drinking

Timepoint [3]

12 month

Primary outcome [4]

Experience of alcohol related harms

Timepoint [4]

12 months

Primary outcome [5]

Symptoms of alcohol abuse, dependence and alcohol use disorder

Timepoint [5]

12 months

Eligibility

Key inclusion criteria

* Grade 7 High School enrolment
* Parental signed informed consent provided

Minimum age

11 Years

Maximum age

13 Years

Sex

Both males and females

Can healthy volunteers participate?

Yes

Key exclusion criteria

* none

Study design

Purpose

Duration

Selection

Timing

Prospective

Statistical methods / analysis

Recruitment

Recruitment status

UNKNOWN

Data analysis

Reason for early stopping/withdrawal

Other reasons

Date of first participant enrolment

Anticipated

Actual

1/03/2010

Date of last participant enrolment

Anticipated

Actual

Date of last data collection

Anticipated

1/12/2021

Actual

Sample size

Target

Accrual to date

Final

1927

Recruitment in Australia

Recruitment state(s)

NSW

Recruitment hospital [1]

University of New South Wales - Sydney

Recruitment postcode(s) [1]

2052 - Sydney

Funding & Sponsors

Primary sponsor type

Other

Name

The University of New South Wales

Address

Country

Ethics approval

Ethics application status

Summary

Brief summary

Parents can positively influence their children's alcohol use. One strategy they use is to provide their children with alcohol, believing it is the best way to teach their children how to drink responsibly. The impact of parental supply is not well understood and may be unintentionally harmful. This study will research the consequences of parental supply within the broader context of parent, child and peer relationships. It will help to determine how parental supply influences the different patterns of adolescent alcohol consumption over time, providing essential information to help parents prevent alcohol misuse in their children. Parents can play a pivotal role in prevention of alcohol misuse, but at present we don't know exactly how.

Trial website

https://clinicaltrials.gov/study/NCT02280551

Trial related presentations / publications

Wadolowski M, Bruno R, Aiken A, Stone C, Najman J, Kypri K, Slade T, Hutchinson D, McBride N, Mattick RP. Sipping, drinking, and early adolescent alcohol consumption: a cautionary note. Alcohol Clin Exp Res. 2015 Feb;39(2):350-4. doi: 10.1111/acer.12613.
Wadolowski M, Hutchinson D, Bruno R, Aiken A, Clare P, Slade T, Najman J, Kypri K, McBride N, Mattick RP. Early Adolescent Alcohol Use: Are Sipping and Drinking Distinct? Alcohol Clin Exp Res. 2015 Sep;39(9):1805-13. doi: 10.1111/acer.12826. Epub 2015 Aug 6.
Wadolowski M, Hutchinson D, Bruno R, Aiken A, Najman JM, Kypri K, Slade T, McBride N, Mattick RP. Parents Who Supply Sips of Alcohol in Early Adolescence: A Prospective Study of Risk Factors. Pediatrics. 2016 Mar;137(3):e20152611. doi: 10.1542/peds.2015-2611. Epub 2016 Feb 26.
Mattick RP, Wadolowski M, Aiken A, Clare PJ, Hutchinson D, Najman J, Slade T, Bruno R, McBride N, Degenhardt L, Kypri K. Parental supply of alcohol and alcohol consumption in adolescence: prospective cohort study. Psychol Med. 2017 Jan;47(2):267-278. doi: 10.1017/S0033291716002373. Epub 2016 Oct 5.
Aiken A, Wadolowski M, Bruno R, Najman J, Kypri K, Slade T, Hutchinson D, McBride N, Mattick RP. Cohort Profile: The Australian Parental Supply of Alcohol Longitudinal Study (APSALS). Int J Epidemiol. 2017 Apr 1;46(2):e6. doi: 10.1093/ije/dyv051.
Aiken A, Clare PJ, Wadolowski M, Hutchinson D, Najman JM, Slade T, Bruno R, McBride N, Kypri K, Mattick RP. Age of Alcohol Initiation and Progression to Binge Drinking in Adolescence: A Prospective Cohort Study. Alcohol Clin Exp Res. 2018 Jan;42(1):100-110. doi: 10.1111/acer.13525. Epub 2017 Nov 21.
Mattick RP, Clare PJ, Aiken A, Wadolowski M, Hutchinson D, Najman J, Slade T, Bruno R, McBride N, Kypri K, Vogl L, Degenhardt L. Association of parental supply of alcohol with adolescent drinking, alcohol-related harms, and alcohol use disorder symptoms: a prospective cohort study. Lancet Public Health. 2018 Feb;3(2):e64-e71. doi: 10.1016/S2468-2667(17)30240-2. Epub 2018 Feb 1. Erratum In: Lancet Public Health. 2018 Mar;3(3):e114. doi: 10.1016/S2468-2667(18)30023-9.
Sharmin S, Kypri K, Wadolowski M, Bruno R, Khanam M, Aiken A, Hutchinson D, M Najman J, Slade T, McBride N, Attia J, P Mattick R. Parent characteristics associated with approval of their children drinking alcohol from ages 13 to 16 years: prospective cohort study. Aust N Z J Public Health. 2018 Aug;42(4):347-353. doi: 10.1111/1753-6405.12811. Epub 2018 Jul 23.
Sharmin S, Kypri K, Wadolowski M, Bruno R, Khanam M, Aiken A, Hutchinson D, Najman JM, Slade T, McBride N, Attia J, Palazzi K, Oldmeadow C, Mattick RP. Parent hazardous drinking and their children's alcohol use in early and mid-adolescence: prospective cohort study. Eur J Public Health. 2019 Aug 1;29(4):736-740. doi: 10.1093/eurpub/ckz029.
Clare PJ, Aiken A, Yuen WS, Peacock A, Boland V, Wadolowski M, Hutchinson D, Najman J, Slade T, Bruno R, McBride N, Degenhardt L, Kypri K, Mattick RP. Parental supply of alcohol as a predictor of adolescent alcohol consumption patterns: A prospective cohort. Drug Alcohol Depend. 2019 Nov 1;204:107529. doi: 10.1016/j.drugalcdep.2019.06.031. Epub 2019 Aug 29.
Clare PJ, Dobbins T, Bruno R, Peacock A, Boland V, Yuen WS, Aiken A, Degenhardt L, Kypri K, Slade T, Hutchinson D, Najman JM, McBride N, Horwood J, McCambridge J, Mattick RP. The overall effect of parental supply of alcohol across adolescence on alcohol-related harms in early adulthood-a prospective cohort study. Addiction. 2020 Oct;115(10):1833-1843. doi: 10.1111/add.15005. Epub 2020 Mar 6.
Boland VC, Clare PJ, Yuen WS, Peacock A, Aiken A, Wadolowski M, Hutchinson D, Najman J, Slade T, Bruno R, McBride N, Degenhardt L, Kypri K, Mattick RP. The association between parental supply of alcohol and supply from other sources to young people: a prospective cohort. Addiction. 2020 Nov;115(11):2140-2147. doi: 10.1111/add.15033. Epub 2020 Mar 24.
Yuen WS, Chan G, Bruno R, Clare P, Mattick R, Aiken A, Boland V, McBride N, McCambridge J, Slade T, Kypri K, Horwood J, Hutchinson D, Najman J, De Torres C, Peacock A. Adolescent Alcohol Use Trajectories: Risk Factors and Adult Outcomes. Pediatrics. 2020 Oct;146(4):e20200440. doi: 10.1542/peds.2020-0440. Epub 2020 Sep 23.
Aiken A, Clare PJ, Boland VC, Degenhardt L, Yuen WS, Hutchinson D, Najman J, McCambridge J, Slade T, McBride N, De Torres C, Wadolowski M, Bruno R, Kypri K, Mattick RP, Peacock A. Parental supply of sips and whole drinks of alcohol to adolescents and associations with binge drinking and alcohol-related harms: A prospective cohort study. Drug Alcohol Depend. 2020 Oct 1;215:108204. doi: 10.1016/j.drugalcdep.2020.108204. Epub 2020 Aug 5.
Yuen WS, Chan G, Bruno R, Clare PJ, Aiken A, Mattick R, Farrell M, Kypri K, Slade T, Hutchinson D, McBride N, McCambridge J, Boland V, Peacock A. Trajectories of alcohol-induced blackouts in adolescence: early risk factors and alcohol use disorder outcomes in early adulthood. Addiction. 2021 Aug;116(8):2039-2048. doi: 10.1111/add.15415. Epub 2021 Feb 1.
Aiken A, Chan G, Yuen WS, Clare PJ, Hutchinson D, McBride N, Najman JM, McCambridge J, Upton E, Slade T, Boland VC, De Torres C, Bruno R, Kypri K, Wadolowski M, Mattick RP, Peacock A. Trajectories of parental and peer supply of alcohol in adolescence and associations with later alcohol consumption and harms: A prospective cohort study. Drug Alcohol Depend. 2022 Aug 1;237:109533. doi: 10.1016/j.drugalcdep.2022.109533. Epub 2022 Jun 11.
Najman JM, Clare PJ, Kypri K, Aiken A, Wadolowski M, Hutchinson D, Slade T, Bruno R, Vogl L, Degenhardt L, Mattick RP. Gender differences in the supply of alcohol to adolescent daughters and sons. Am J Drug Alcohol Abuse. 2021 Jul 4;47(4):508-520. doi: 10.1080/00952990.2021.1927066. Epub 2021 Aug 12.

Public notes

Contacts

Principal investigator

Name

RICHARD P MATTICK, PhD

Address

NATIONAL DRUG AND ALCOHOL RESEARCH CENTRE, UNSW AUSTRALIA

Country

Phone

Fax

Contact person for public queries

Name

Address

Country

Phone

Fax

Contact person for scientific queries

No information has been provided regarding IPD availability

What supporting documents are/will be available?

No Supporting Document Provided

Results publications and other study-related documents

Type	Citations or Other Details
Journal	Wadolowski M, Bruno R, Aiken A, Stone C, Najman J,... [More Details]
Journal	Wadolowski M, Hutchinson D, Bruno R, Aiken A, Clar... [More Details]
Journal	Wadolowski M, Hutchinson D, Bruno R, Aiken A, Najm... [More Details]
Journal	Mattick RP, Wadolowski M, Aiken A, Clare PJ, Hutch... [More Details]
Journal	Aiken A, Wadolowski M, Bruno R, Najman J, Kypri K,... [More Details]
Journal	Aiken A, Clare PJ, Wadolowski M, Hutchinson D, Naj... [More Details]
Journal	Mattick RP, Clare PJ, Aiken A, Wadolowski M, Hutch... [More Details]
Journal	Sharmin S, Kypri K, Wadolowski M, Bruno R, Khanam ... [More Details]
Journal	Sharmin S, Kypri K, Wadolowski M, Bruno R, Khanam ... [More Details]
Journal	Clare PJ, Aiken A, Yuen WS, Peacock A, Boland V, W... [More Details]
Journal	Clare PJ, Dobbins T, Bruno R, Peacock A, Boland V,... [More Details]
Journal	Boland VC, Clare PJ, Yuen WS, Peacock A, Aiken A, ... [More Details]
Journal	Yuen WS, Chan G, Bruno R, Clare P, Mattick R, Aike... [More Details]
Journal	Aiken A, Clare PJ, Boland VC, Degenhardt L, Yuen W... [More Details]
Journal	Yuen WS, Chan G, Bruno R, Clare PJ, Aiken A, Matti... [More Details]

Results not provided in https://clinicaltrials.gov/study/NCT02280551

Trial Review

Registering a new trial?

For full trial details, please see the original record at https://clinicaltrials.gov/study/NCT02280551