Please note that the copy function is not enabled for this field.
If you wish to
modify
existing outcomes, please copy and paste the current outcome text into the Update field.
LOGIN
CREATE ACCOUNT
LOGIN
CREATE ACCOUNT
MY TRIALS
REGISTER TRIAL
FAQs
HINTS AND TIPS
DEFINITIONS
Trial Review
The ANZCTR website will be unavailable from 1pm until 3pm (AEDT) on Wednesday the 30th of October for website maintenance. Please be sure to log out of the system in order to avoid any loss of data.
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been endorsed by the ANZCTR. Before participating in a study, talk to your health care provider and refer to this
information for consumers
Download to PDF
Trial details imported from ClinicalTrials.gov
For full trial details, please see the original record at
https://clinicaltrials.gov/study/NCT02322762
Registration number
NCT02322762
Ethics application status
Date submitted
19/12/2014
Date registered
23/12/2014
Date last updated
9/06/2022
Titles & IDs
Public title
DISCOVERing Treatment Reality of Type 2 Diabetes in Real World Settings
Query!
Scientific title
DISCOVERing Treatment Reality of Type 2 Diabetes in Real World Settings
Query!
Secondary ID [1]
0
0
D1690R00002
Query!
Universal Trial Number (UTN)
Query!
Trial acronym
DISCOVER
Query!
Linked study record
Query!
Health condition
Health condition(s) or problem(s) studied:
Type 2 Diabetes Mellitus
0
0
Query!
Condition category
Condition code
Metabolic and Endocrine
0
0
0
0
Query!
Diabetes
Query!
Intervention/exposure
Study type
Observational
Query!
Patient registry
Query!
Target follow-up duration
Query!
Target follow-up type
Query!
Description of intervention(s) / exposure
One single cohort. - One single cohort of patients with type 2 diabetes mellitus initiating their second line anti-diabetic therapy after first line anti-diabetic therapy.
Query!
Comparator / control treatment
Query!
Control group
Query!
Outcomes
Primary outcome [1]
0
0
Anti-diabetic treatments prescribed by physicians in a real-world setting.
Query!
Assessment method [1]
0
0
The drugs (or their combinations) prescribed by physicians to patients initiating a 2nd line anti-diabetic treatment in a real-world setting will be described at inclusion and during 3 years follow-up.
Query!
Timepoint [1]
0
0
Up to 3 Years
Query!
Secondary outcome [1]
0
0
Disease control in terms of achieving HbA1c target goals and reducing body weight and blood pressure.
Query!
Assessment method [1]
0
0
Query!
Timepoint [1]
0
0
Up to 3 years
Query!
Secondary outcome [2]
0
0
Changes in anti-diabetic treatments
Query!
Assessment method [2]
0
0
Query!
Timepoint [2]
0
0
Up to 3 years
Query!
Secondary outcome [3]
0
0
Disease progression (incidence of microvascular and macrovascular complications).
Query!
Assessment method [3]
0
0
Query!
Timepoint [3]
0
0
Up to 3 years
Query!
Secondary outcome [4]
0
0
Incidence of hypoglycemic events.
Query!
Assessment method [4]
0
0
Query!
Timepoint [4]
0
0
Up to 3 years
Query!
Secondary outcome [5]
0
0
Quality of Life, using Patient Reported Outcomes questionnaires.
Query!
Assessment method [5]
0
0
Query!
Timepoint [5]
0
0
Up to 3 years
Query!
Secondary outcome [6]
0
0
Use of Healthcare resources.
Query!
Assessment method [6]
0
0
Query!
Timepoint [6]
0
0
Up to 3 years
Query!
Eligibility
Key inclusion criteria
1. Provision of subject informed consent
2. Female or male aged 18 years and over
3. Diagnosed with type 2 diabetes mellitus
4. Initiating a second line anti-diabetic therapy, either as add-on, or switching from one monotherapy to another.
Query!
Minimum age
18
Years
Query!
Query!
Maximum age
No limit
Query!
Query!
Sex
Both males and females
Query!
Can healthy volunteers participate?
No
Query!
Key exclusion criteria
1. Diagnosis of type 1 diabetes mellitus
2. Patient is pregnant
3. Patients initiating a dual therapy after having previously received two different lines of monotherapy before (e.g.: Metformin ? SU (Sulphonylureas) ? SU+Add-on)
4. Current treatment with chemotherapy, oral or iv steroids
5. Patient is on dialysis or has had a renal transplant
6. The patient is taking insulin as first line treatment
7. The patient is taking dual therapy or a fixed dose combination treatment as first line treatment.
8. The patient is taking herbal remedies / natural medicines as first line treatment
9. Participation in an interventional trial
10. Presence of any condition/circumstance which in the opinion of the investigator could significantly limit the complete follow up of the patient for 3 years (e.g. lifethreatening co-morbidities, tourist, non-native speaker or does not understand the local language where interpreter services are not reliably available, psychiatric disturbances, dementia, alcohol or drug abuse).
11. Not willing to sign the informed consent.
Query!
Study design
Purpose
Query!
Duration
Query!
Selection
Query!
Timing
Prospective
Query!
Statistical methods / analysis
Query!
Recruitment
Recruitment status
Completed
Query!
Data analysis
Query!
Reason for early stopping/withdrawal
Query!
Other reasons
Query!
Date of first participant enrolment
Anticipated
Query!
Actual
30/12/2014
Query!
Date of last participant enrolment
Anticipated
Query!
Actual
Query!
Date of last data collection
Anticipated
Query!
Actual
21/08/2019
Query!
Sample size
Target
Query!
Accrual to date
Query!
Final
15992
Query!
Recruitment in Australia
Recruitment state(s)
Query!
Recruitment hospital [1]
0
0
Research Site - Blacktown
Query!
Recruitment hospital [2]
0
0
Research Site - Burwood
Query!
Recruitment hospital [3]
0
0
Research Site - Castle Hill
Query!
Recruitment hospital [4]
0
0
Research Site - Coorparoo
Query!
Recruitment hospital [5]
0
0
Research Site - Corio
Query!
Recruitment hospital [6]
0
0
Research Site - Cowra
Query!
Recruitment hospital [7]
0
0
Research Site - Edmonton
Query!
Recruitment hospital [8]
0
0
Research Site - Forbes
Query!
Recruitment hospital [9]
0
0
Research Site - Garran
Query!
Recruitment hospital [10]
0
0
Research Site - Ipswich
Query!
Recruitment hospital [11]
0
0
Research Site - Melbourne
Query!
Recruitment hospital [12]
0
0
Research Site - Sherwood
Query!
Recruitment hospital [13]
0
0
Research Site - Smithfield
Query!
Recruitment hospital [14]
0
0
Research Site - South Lake
Query!
Recruitment postcode(s) [1]
0
0
- Blacktown
Query!
Recruitment postcode(s) [2]
0
0
- Burwood
Query!
Recruitment postcode(s) [3]
0
0
- Castle Hill
Query!
Recruitment postcode(s) [4]
0
0
- Coorparoo
Query!
Recruitment postcode(s) [5]
0
0
- Corio
Query!
Recruitment postcode(s) [6]
0
0
- Cowra
Query!
Recruitment postcode(s) [7]
0
0
- Edmonton
Query!
Recruitment postcode(s) [8]
0
0
- Forbes
Query!
Recruitment postcode(s) [9]
0
0
- Garran
Query!
Recruitment postcode(s) [10]
0
0
- Ipswich
Query!
Recruitment postcode(s) [11]
0
0
- Melbourne
Query!
Recruitment postcode(s) [12]
0
0
- Sherwood
Query!
Recruitment postcode(s) [13]
0
0
- Smithfield
Query!
Recruitment postcode(s) [14]
0
0
- South Lake
Query!
Recruitment outside Australia
Country [1]
0
0
Algeria
Query!
State/province [1]
0
0
Alger
Query!
Country [2]
0
0
Algeria
Query!
State/province [2]
0
0
Algiers
Query!
Country [3]
0
0
Algeria
Query!
State/province [3]
0
0
Batna
Query!
Country [4]
0
0
Algeria
Query!
State/province [4]
0
0
Blida
Query!
Country [5]
0
0
Algeria
Query!
State/province [5]
0
0
Constantine
Query!
Country [6]
0
0
Algeria
Query!
State/province [6]
0
0
Oran
Query!
Country [7]
0
0
Algeria
Query!
State/province [7]
0
0
Setif
Query!
Country [8]
0
0
Argentina
Query!
State/province [8]
0
0
Chacabuco
Query!
Country [9]
0
0
Argentina
Query!
State/province [9]
0
0
Ciudad Autonoma Buenos Aires
Query!
Country [10]
0
0
Argentina
Query!
State/province [10]
0
0
Ciudad Autonoma de Buenos Aires
Query!
Country [11]
0
0
Argentina
Query!
State/province [11]
0
0
Cordoba
Query!
Country [12]
0
0
Argentina
Query!
State/province [12]
0
0
Corrientes
Query!
Country [13]
0
0
Argentina
Query!
State/province [13]
0
0
Parana
Query!
Country [14]
0
0
Argentina
Query!
State/province [14]
0
0
Rosario
Query!
Country [15]
0
0
Argentina
Query!
State/province [15]
0
0
San Miguel de Tucuman
Query!
Country [16]
0
0
Argentina
Query!
State/province [16]
0
0
Santa Fe
Query!
Country [17]
0
0
Austria
Query!
State/province [17]
0
0
Feldbach
Query!
Country [18]
0
0
Austria
Query!
State/province [18]
0
0
Graz
Query!
Country [19]
0
0
Austria
Query!
State/province [19]
0
0
Innsbruck
Query!
Country [20]
0
0
Austria
Query!
State/province [20]
0
0
Linz
Query!
Country [21]
0
0
Austria
Query!
State/province [21]
0
0
Salzburg
Query!
Country [22]
0
0
Austria
Query!
State/province [22]
0
0
St.Veit im Pongau
Query!
Country [23]
0
0
Austria
Query!
State/province [23]
0
0
Stankt Stefan Ob Stainz
Query!
Country [24]
0
0
Austria
Query!
State/province [24]
0
0
Vienna
Query!
Country [25]
0
0
Austria
Query!
State/province [25]
0
0
Wien
Query!
Country [26]
0
0
Bahrain
Query!
State/province [26]
0
0
Bahrain
Query!
Country [27]
0
0
Brazil
Query!
State/province [27]
0
0
Belo Horizonte
Query!
Country [28]
0
0
Brazil
Query!
State/province [28]
0
0
Brasilia
Query!
Country [29]
0
0
Brazil
Query!
State/province [29]
0
0
Campina Grande do Sul
Query!
Country [30]
0
0
Brazil
Query!
State/province [30]
0
0
Campinas
Query!
Country [31]
0
0
Brazil
Query!
State/province [31]
0
0
Curitiba
Query!
Country [32]
0
0
Brazil
Query!
State/province [32]
0
0
Fortaleza
Query!
Country [33]
0
0
Brazil
Query!
State/province [33]
0
0
Juiz de Fora
Query!
Country [34]
0
0
Brazil
Query!
State/province [34]
0
0
Porto Alegre
Query!
Country [35]
0
0
Brazil
Query!
State/province [35]
0
0
Rio de Janeiro
Query!
Country [36]
0
0
Brazil
Query!
State/province [36]
0
0
Santa Maria
Query!
Country [37]
0
0
Brazil
Query!
State/province [37]
0
0
Sao Jose do Rio Preto
Query!
Country [38]
0
0
Brazil
Query!
State/province [38]
0
0
Sao Jose dos Campos
Query!
Country [39]
0
0
Brazil
Query!
State/province [39]
0
0
Sao Paulo
Query!
Country [40]
0
0
China
Query!
State/province [40]
0
0
Beijing
Query!
Country [41]
0
0
China
Query!
State/province [41]
0
0
Changsha
Query!
Country [42]
0
0
China
Query!
State/province [42]
0
0
Chengdu
Query!
Country [43]
0
0
China
Query!
State/province [43]
0
0
Chenzhou
Query!
Country [44]
0
0
China
Query!
State/province [44]
0
0
Chongqing
Query!
Country [45]
0
0
China
Query!
State/province [45]
0
0
Fuzhou
Query!
Country [46]
0
0
China
Query!
State/province [46]
0
0
Guangzhou
Query!
Country [47]
0
0
China
Query!
State/province [47]
0
0
Guiyang
Query!
Country [48]
0
0
China
Query!
State/province [48]
0
0
Hefei
Query!
Country [49]
0
0
China
Query!
State/province [49]
0
0
Kunming
Query!
Country [50]
0
0
China
Query!
State/province [50]
0
0
Lanzhou
Query!
Country [51]
0
0
China
Query!
State/province [51]
0
0
Nanjing
Query!
Country [52]
0
0
China
Query!
State/province [52]
0
0
Panjin
Query!
Country [53]
0
0
China
Query!
State/province [53]
0
0
Shanghai
Query!
Country [54]
0
0
China
Query!
State/province [54]
0
0
Shantou
Query!
Country [55]
0
0
China
Query!
State/province [55]
0
0
Shijiazhuang
Query!
Country [56]
0
0
China
Query!
State/province [56]
0
0
Shiyan
Query!
Country [57]
0
0
China
Query!
State/province [57]
0
0
Suzhou City
Query!
Country [58]
0
0
China
Query!
State/province [58]
0
0
Tianjin
Query!
Country [59]
0
0
China
Query!
State/province [59]
0
0
Urumchi
Query!
Country [60]
0
0
China
Query!
State/province [60]
0
0
Wuhan
Query!
Country [61]
0
0
China
Query!
State/province [61]
0
0
Wuxi
Query!
Country [62]
0
0
Colombia
Query!
State/province [62]
0
0
Barranquilla
Query!
Country [63]
0
0
Colombia
Query!
State/province [63]
0
0
Bogota
Query!
Country [64]
0
0
Colombia
Query!
State/province [64]
0
0
Cali
Query!
Country [65]
0
0
Colombia
Query!
State/province [65]
0
0
Manizales
Query!
Country [66]
0
0
Colombia
Query!
State/province [66]
0
0
Medellin
Query!
Country [67]
0
0
Costa Rica
Query!
State/province [67]
0
0
Cartago
Query!
Country [68]
0
0
Costa Rica
Query!
State/province [68]
0
0
Heredia
Query!
Country [69]
0
0
Costa Rica
Query!
State/province [69]
0
0
San Jose
Query!
Country [70]
0
0
Czechia
Query!
State/province [70]
0
0
Benatky nad Jizerou
Query!
Country [71]
0
0
Czechia
Query!
State/province [71]
0
0
Beroun
Query!
Country [72]
0
0
Czechia
Query!
State/province [72]
0
0
Broumov
Query!
Country [73]
0
0
Czechia
Query!
State/province [73]
0
0
Dolni Brezany
Query!
Country [74]
0
0
Czechia
Query!
State/province [74]
0
0
Karlovy Vary
Query!
Country [75]
0
0
Czechia
Query!
State/province [75]
0
0
Krnov
Query!
Country [76]
0
0
Czechia
Query!
State/province [76]
0
0
Litomerice
Query!
Country [77]
0
0
Czechia
Query!
State/province [77]
0
0
Nachod
Query!
Country [78]
0
0
Czechia
Query!
State/province [78]
0
0
Olomouc
Query!
Country [79]
0
0
Czechia
Query!
State/province [79]
0
0
Ostrava
Query!
Country [80]
0
0
Czechia
Query!
State/province [80]
0
0
Plzen
Query!
Country [81]
0
0
Czechia
Query!
State/province [81]
0
0
Praha
Query!
Country [82]
0
0
Czechia
Query!
State/province [82]
0
0
Uherske Hradiste
Query!
Country [83]
0
0
Czechia
Query!
State/province [83]
0
0
Ujezd U Brna
Query!
Country [84]
0
0
Egypt
Query!
State/province [84]
0
0
Alexandria
Query!
Country [85]
0
0
Egypt
Query!
State/province [85]
0
0
Asyut
Query!
Country [86]
0
0
Egypt
Query!
State/province [86]
0
0
Cairo
Query!
Country [87]
0
0
Egypt
Query!
State/province [87]
0
0
Giza
Query!
Country [88]
0
0
Egypt
Query!
State/province [88]
0
0
Heliopolis
Query!
Country [89]
0
0
Egypt
Query!
State/province [89]
0
0
Mansoura
Query!
Country [90]
0
0
Egypt
Query!
State/province [90]
0
0
Minya
Query!
Country [91]
0
0
Egypt
Query!
State/province [91]
0
0
Tanta
Query!
Country [92]
0
0
India
Query!
State/province [92]
0
0
Bangalore
Query!
Country [93]
0
0
India
Query!
State/province [93]
0
0
Chandigarh
Query!
Country [94]
0
0
India
Query!
State/province [94]
0
0
Chennai
Query!
Country [95]
0
0
India
Query!
State/province [95]
0
0
Coimbatore
Query!
Country [96]
0
0
India
Query!
State/province [96]
0
0
Delhi
Query!
Country [97]
0
0
India
Query!
State/province [97]
0
0
Ghaziabad
Query!
Country [98]
0
0
India
Query!
State/province [98]
0
0
Gurgaon
Query!
Country [99]
0
0
India
Query!
State/province [99]
0
0
Hyderabad
Query!
Country [100]
0
0
India
Query!
State/province [100]
0
0
Indore
Query!
Country [101]
0
0
India
Query!
State/province [101]
0
0
Jaipur
Query!
Country [102]
0
0
India
Query!
State/province [102]
0
0
Kanpur
Query!
Country [103]
0
0
India
Query!
State/province [103]
0
0
Karnal
Query!
Country [104]
0
0
India
Query!
State/province [104]
0
0
Kolkata
Query!
Country [105]
0
0
India
Query!
State/province [105]
0
0
Mangalore
Query!
Country [106]
0
0
India
Query!
State/province [106]
0
0
Mumbai
Query!
Country [107]
0
0
India
Query!
State/province [107]
0
0
Nagpur
Query!
Country [108]
0
0
India
Query!
State/province [108]
0
0
Noida
Query!
Country [109]
0
0
India
Query!
State/province [109]
0
0
Pune
Query!
Country [110]
0
0
India
Query!
State/province [110]
0
0
Trivandrum
Query!
Country [111]
0
0
Indonesia
Query!
State/province [111]
0
0
Balikpapan
Query!
Country [112]
0
0
Indonesia
Query!
State/province [112]
0
0
Banda Aceh
Query!
Country [113]
0
0
Indonesia
Query!
State/province [113]
0
0
Batu
Query!
Country [114]
0
0
Indonesia
Query!
State/province [114]
0
0
Bekasi Timur
Query!
Country [115]
0
0
Indonesia
Query!
State/province [115]
0
0
Denpasar
Query!
Country [116]
0
0
Indonesia
Query!
State/province [116]
0
0
Jakarta
Query!
Country [117]
0
0
Indonesia
Query!
State/province [117]
0
0
Malang
Query!
Country [118]
0
0
Indonesia
Query!
State/province [118]
0
0
Manado
Query!
Country [119]
0
0
Indonesia
Query!
State/province [119]
0
0
Padang
Query!
Country [120]
0
0
Italy
Query!
State/province [120]
0
0
Foggia
Query!
Country [121]
0
0
Italy
Query!
State/province [121]
0
0
Garbagnate Milanese
Query!
Country [122]
0
0
Italy
Query!
State/province [122]
0
0
Livorno
Query!
Country [123]
0
0
Italy
Query!
State/province [123]
0
0
Mariano Comense
Query!
Country [124]
0
0
Italy
Query!
State/province [124]
0
0
Parma
Query!
Country [125]
0
0
Italy
Query!
State/province [125]
0
0
Pavia
Query!
Country [126]
0
0
Italy
Query!
State/province [126]
0
0
Pisa
Query!
Country [127]
0
0
Italy
Query!
State/province [127]
0
0
Potenza
Query!
Country [128]
0
0
Italy
Query!
State/province [128]
0
0
Rimini
Query!
Country [129]
0
0
Italy
Query!
State/province [129]
0
0
Roma
Query!
Country [130]
0
0
Italy
Query!
State/province [130]
0
0
Sesto San Giovanni
Query!
Country [131]
0
0
Jordan
Query!
State/province [131]
0
0
Amman
Query!
Country [132]
0
0
Jordan
Query!
State/province [132]
0
0
Az Zarqaa
Query!
Country [133]
0
0
Jordan
Query!
State/province [133]
0
0
Irbid
Query!
Country [134]
0
0
Korea, Republic of
Query!
State/province [134]
0
0
Bucheon-si
Query!
Country [135]
0
0
Korea, Republic of
Query!
State/province [135]
0
0
Cheonan-si
Query!
Country [136]
0
0
Korea, Republic of
Query!
State/province [136]
0
0
Chuncheon-si
Query!
Country [137]
0
0
Korea, Republic of
Query!
State/province [137]
0
0
Daejeon
Query!
Country [138]
0
0
Korea, Republic of
Query!
State/province [138]
0
0
Goyang-si
Query!
Country [139]
0
0
Korea, Republic of
Query!
State/province [139]
0
0
Gwangmyeong Si
Query!
Country [140]
0
0
Korea, Republic of
Query!
State/province [140]
0
0
Iksan
Query!
Country [141]
0
0
Korea, Republic of
Query!
State/province [141]
0
0
Jeju Special Self-Governing Province
Query!
Country [142]
0
0
Korea, Republic of
Query!
State/province [142]
0
0
Seongnam-si
Query!
Country [143]
0
0
Korea, Republic of
Query!
State/province [143]
0
0
Seoul
Query!
Country [144]
0
0
Kuwait
Query!
State/province [144]
0
0
Kuwait City
Query!
Country [145]
0
0
Lebanon
Query!
State/province [145]
0
0
Beirut
Query!
Country [146]
0
0
Lebanon
Query!
State/province [146]
0
0
Chtoura
Query!
Country [147]
0
0
Lebanon
Query!
State/province [147]
0
0
Hamra
Query!
Country [148]
0
0
Lebanon
Query!
State/province [148]
0
0
Jbeil
Query!
Country [149]
0
0
Lebanon
Query!
State/province [149]
0
0
Mazraat Yachouh
Query!
Country [150]
0
0
Lebanon
Query!
State/province [150]
0
0
Saida
Query!
Country [151]
0
0
Lebanon
Query!
State/province [151]
0
0
Tripoli
Query!
Country [152]
0
0
Lebanon
Query!
State/province [152]
0
0
Tyre
Query!
Country [153]
0
0
Malaysia
Query!
State/province [153]
0
0
Air Itam
Query!
Country [154]
0
0
Malaysia
Query!
State/province [154]
0
0
Alor Setar
Query!
Country [155]
0
0
Malaysia
Query!
State/province [155]
0
0
Ipoh
Query!
Country [156]
0
0
Malaysia
Query!
State/province [156]
0
0
Johor Bahru
Query!
Country [157]
0
0
Malaysia
Query!
State/province [157]
0
0
Kelantan
Query!
Country [158]
0
0
Malaysia
Query!
State/province [158]
0
0
Kuala Krai
Query!
Country [159]
0
0
Malaysia
Query!
State/province [159]
0
0
Masjid Tanah
Query!
Country [160]
0
0
Malaysia
Query!
State/province [160]
0
0
Miri
Query!
Country [161]
0
0
Malaysia
Query!
State/province [161]
0
0
Perak
Query!
Country [162]
0
0
Malaysia
Query!
State/province [162]
0
0
Sandakan
Query!
Country [163]
0
0
Malaysia
Query!
State/province [163]
0
0
Seremban
Query!
Country [164]
0
0
Mexico
Query!
State/province [164]
0
0
Acapulco de Juarez
Query!
Country [165]
0
0
Mexico
Query!
State/province [165]
0
0
Aguascalientes
Query!
Country [166]
0
0
Mexico
Query!
State/province [166]
0
0
Chihuahua
Query!
Country [167]
0
0
Mexico
Query!
State/province [167]
0
0
Guadalajara
Query!
Country [168]
0
0
Mexico
Query!
State/province [168]
0
0
Mexico
Query!
Country [169]
0
0
Mexico
Query!
State/province [169]
0
0
Monterrey
Query!
Country [170]
0
0
Mexico
Query!
State/province [170]
0
0
San Juan del Rio
Query!
Country [171]
0
0
Mexico
Query!
State/province [171]
0
0
Tamaulipas
Query!
Country [172]
0
0
Mexico
Query!
State/province [172]
0
0
Zapopan
Query!
Country [173]
0
0
Netherlands
Query!
State/province [173]
0
0
Almelo
Query!
Country [174]
0
0
Netherlands
Query!
State/province [174]
0
0
Alpen Aan Den Rijn
Query!
Country [175]
0
0
Netherlands
Query!
State/province [175]
0
0
Amersfoort
Query!
Country [176]
0
0
Netherlands
Query!
State/province [176]
0
0
Amsterdam
Query!
Country [177]
0
0
Netherlands
Query!
State/province [177]
0
0
De Bilt
Query!
Country [178]
0
0
Netherlands
Query!
State/province [178]
0
0
Den Haag
Query!
Country [179]
0
0
Netherlands
Query!
State/province [179]
0
0
Doetinchem
Query!
Country [180]
0
0
Netherlands
Query!
State/province [180]
0
0
Dordrecht
Query!
Country [181]
0
0
Netherlands
Query!
State/province [181]
0
0
Dorst
Query!
Country [182]
0
0
Netherlands
Query!
State/province [182]
0
0
Elst
Query!
Country [183]
0
0
Netherlands
Query!
State/province [183]
0
0
Enschede
Query!
Country [184]
0
0
Netherlands
Query!
State/province [184]
0
0
Etten-Leur
Query!
Country [185]
0
0
Netherlands
Query!
State/province [185]
0
0
Garderen
Query!
Country [186]
0
0
Netherlands
Query!
State/province [186]
0
0
Geleen
Query!
Country [187]
0
0
Netherlands
Query!
State/province [187]
0
0
Gouda
Query!
Country [188]
0
0
Netherlands
Query!
State/province [188]
0
0
Hoogezand
Query!
Country [189]
0
0
Netherlands
Query!
State/province [189]
0
0
Katwijk
Query!
Country [190]
0
0
Netherlands
Query!
State/province [190]
0
0
Kerkrade
Query!
Country [191]
0
0
Netherlands
Query!
State/province [191]
0
0
Kloosterhaar
Query!
Country [192]
0
0
Netherlands
Query!
State/province [192]
0
0
Landgraaf
Query!
Country [193]
0
0
Netherlands
Query!
State/province [193]
0
0
Luttenberg
Query!
Country [194]
0
0
Netherlands
Query!
State/province [194]
0
0
Nijverdal
Query!
Country [195]
0
0
Netherlands
Query!
State/province [195]
0
0
Oisterwijk
Query!
Country [196]
0
0
Netherlands
Query!
State/province [196]
0
0
Roermond
Query!
Country [197]
0
0
Netherlands
Query!
State/province [197]
0
0
Soerendonk
Query!
Country [198]
0
0
Netherlands
Query!
State/province [198]
0
0
Steenbergen
Query!
Country [199]
0
0
Netherlands
Query!
State/province [199]
0
0
Utrecht
Query!
Country [200]
0
0
Netherlands
Query!
State/province [200]
0
0
Vaassen
Query!
Country [201]
0
0
Netherlands
Query!
State/province [201]
0
0
Voerendaal
Query!
Country [202]
0
0
Netherlands
Query!
State/province [202]
0
0
Wamel
Query!
Country [203]
0
0
Netherlands
Query!
State/province [203]
0
0
Zoetermeer
Query!
Country [204]
0
0
Netherlands
Query!
State/province [204]
0
0
Zundert
Query!
Country [205]
0
0
Oman
Query!
State/province [205]
0
0
Muscat
Query!
Country [206]
0
0
Panama
Query!
State/province [206]
0
0
Calle
Query!
Country [207]
0
0
Panama
Query!
State/province [207]
0
0
Cocle
Query!
Country [208]
0
0
Poland
Query!
State/province [208]
0
0
Chorzow
Query!
Country [209]
0
0
Poland
Query!
State/province [209]
0
0
Elblag
Query!
Country [210]
0
0
Poland
Query!
State/province [210]
0
0
Gdansk
Query!
Country [211]
0
0
Poland
Query!
State/province [211]
0
0
Katowice
Query!
Country [212]
0
0
Poland
Query!
State/province [212]
0
0
Krakow
Query!
Country [213]
0
0
Poland
Query!
State/province [213]
0
0
Lodz
Query!
Country [214]
0
0
Poland
Query!
State/province [214]
0
0
Lublin
Query!
Country [215]
0
0
Poland
Query!
State/province [215]
0
0
Parczew
Query!
Country [216]
0
0
Poland
Query!
State/province [216]
0
0
Rzeszow
Query!
Country [217]
0
0
Poland
Query!
State/province [217]
0
0
Zabrze
Query!
Country [218]
0
0
Poland
Query!
State/province [218]
0
0
Zgierz
Query!
Country [219]
0
0
Russian Federation
Query!
State/province [219]
0
0
Arkhangelsk
Query!
Country [220]
0
0
Russian Federation
Query!
State/province [220]
0
0
Barnaul
Query!
Country [221]
0
0
Russian Federation
Query!
State/province [221]
0
0
Moscow
Query!
Country [222]
0
0
Russian Federation
Query!
State/province [222]
0
0
Nizhniy Novgorod
Query!
Country [223]
0
0
Russian Federation
Query!
State/province [223]
0
0
Novosibirsk
Query!
Country [224]
0
0
Russian Federation
Query!
State/province [224]
0
0
Rostov-on-Don
Query!
Country [225]
0
0
Russian Federation
Query!
State/province [225]
0
0
Sankt Petersburg
Query!
Country [226]
0
0
Russian Federation
Query!
State/province [226]
0
0
Saratov
Query!
Country [227]
0
0
Russian Federation
Query!
State/province [227]
0
0
Sestroretsk
Query!
Country [228]
0
0
Russian Federation
Query!
State/province [228]
0
0
Stavropol
Query!
Country [229]
0
0
Russian Federation
Query!
State/province [229]
0
0
Yaroslavl
Query!
Country [230]
0
0
Saudi Arabia
Query!
State/province [230]
0
0
Abha
Query!
Country [231]
0
0
Saudi Arabia
Query!
State/province [231]
0
0
Al Jouf
Query!
Country [232]
0
0
Saudi Arabia
Query!
State/province [232]
0
0
Jeddah
Query!
Country [233]
0
0
Saudi Arabia
Query!
State/province [233]
0
0
Khamis Mushayt
Query!
Country [234]
0
0
Saudi Arabia
Query!
State/province [234]
0
0
Riyadh
Query!
Country [235]
0
0
South Africa
Query!
State/province [235]
0
0
Alberton
Query!
Country [236]
0
0
South Africa
Query!
State/province [236]
0
0
Cape Town
Query!
Country [237]
0
0
South Africa
Query!
State/province [237]
0
0
Durban
Query!
Country [238]
0
0
South Africa
Query!
State/province [238]
0
0
Johannesburg
Query!
Country [239]
0
0
South Africa
Query!
State/province [239]
0
0
Lenasia
Query!
Country [240]
0
0
South Africa
Query!
State/province [240]
0
0
Merebank
Query!
Country [241]
0
0
South Africa
Query!
State/province [241]
0
0
Midstream
Query!
Country [242]
0
0
South Africa
Query!
State/province [242]
0
0
Moloto
Query!
Country [243]
0
0
South Africa
Query!
State/province [243]
0
0
Port Elizabeth
Query!
Country [244]
0
0
South Africa
Query!
State/province [244]
0
0
Pretoria
Query!
Country [245]
0
0
South Africa
Query!
State/province [245]
0
0
Umkomaas
Query!
Country [246]
0
0
Spain
Query!
State/province [246]
0
0
Barcelona
Query!
Country [247]
0
0
Spain
Query!
State/province [247]
0
0
Cadiz
Query!
Country [248]
0
0
Spain
Query!
State/province [248]
0
0
Elche
Query!
Country [249]
0
0
Spain
Query!
State/province [249]
0
0
Espinardo
Query!
Country [250]
0
0
Spain
Query!
State/province [250]
0
0
Madrid
Query!
Country [251]
0
0
Spain
Query!
State/province [251]
0
0
Mostoles
Query!
Country [252]
0
0
Spain
Query!
State/province [252]
0
0
Salamanca
Query!
Country [253]
0
0
Spain
Query!
State/province [253]
0
0
Sanlucar de Barrameda
Query!
Country [254]
0
0
Spain
Query!
State/province [254]
0
0
Segovia
Query!
Country [255]
0
0
Spain
Query!
State/province [255]
0
0
Sevilla
Query!
Country [256]
0
0
Spain
Query!
State/province [256]
0
0
Valencia
Query!
Country [257]
0
0
Taiwan
Query!
State/province [257]
0
0
Changhua
Query!
Country [258]
0
0
Taiwan
Query!
State/province [258]
0
0
Kaohsiung
Query!
Country [259]
0
0
Taiwan
Query!
State/province [259]
0
0
New Taipei City
Query!
Country [260]
0
0
Taiwan
Query!
State/province [260]
0
0
Taichung City
Query!
Country [261]
0
0
Taiwan
Query!
State/province [261]
0
0
Taichung
Query!
Country [262]
0
0
Taiwan
Query!
State/province [262]
0
0
Tainan City
Query!
Country [263]
0
0
Taiwan
Query!
State/province [263]
0
0
Tainan
Query!
Country [264]
0
0
Taiwan
Query!
State/province [264]
0
0
Taipei
Query!
Country [265]
0
0
Tunisia
Query!
State/province [265]
0
0
Gabes
Query!
Country [266]
0
0
Tunisia
Query!
State/province [266]
0
0
Kairaouane
Query!
Country [267]
0
0
Tunisia
Query!
State/province [267]
0
0
La Soukra
Query!
Country [268]
0
0
Tunisia
Query!
State/province [268]
0
0
Mahdia
Query!
Country [269]
0
0
Tunisia
Query!
State/province [269]
0
0
Mont Fleury
Query!
Country [270]
0
0
Tunisia
Query!
State/province [270]
0
0
Montfleury
Query!
Country [271]
0
0
Tunisia
Query!
State/province [271]
0
0
Mutuelleville
Query!
Country [272]
0
0
Tunisia
Query!
State/province [272]
0
0
Nabeul
Query!
Country [273]
0
0
Tunisia
Query!
State/province [273]
0
0
Sfax
Query!
Country [274]
0
0
Tunisia
Query!
State/province [274]
0
0
Sousse
Query!
Country [275]
0
0
Tunisia
Query!
State/province [275]
0
0
Tunis Belvedere
Query!
Country [276]
0
0
Tunisia
Query!
State/province [276]
0
0
Tunis
Query!
Country [277]
0
0
Turkey
Query!
State/province [277]
0
0
Adana
Query!
Country [278]
0
0
Turkey
Query!
State/province [278]
0
0
Afyonkarahisar
Query!
Country [279]
0
0
Turkey
Query!
State/province [279]
0
0
Antalya
Query!
Country [280]
0
0
Turkey
Query!
State/province [280]
0
0
Canakkale
Query!
Country [281]
0
0
Turkey
Query!
State/province [281]
0
0
Corum
Query!
Country [282]
0
0
Turkey
Query!
State/province [282]
0
0
Denizli
Query!
Country [283]
0
0
Turkey
Query!
State/province [283]
0
0
Diyarbakir
Query!
Country [284]
0
0
Turkey
Query!
State/province [284]
0
0
Duzce
Query!
Country [285]
0
0
Turkey
Query!
State/province [285]
0
0
Elazig
Query!
Country [286]
0
0
Turkey
Query!
State/province [286]
0
0
Gaziantep
Query!
Country [287]
0
0
Turkey
Query!
State/province [287]
0
0
Hatay
Query!
Country [288]
0
0
Turkey
Query!
State/province [288]
0
0
Istanbul
Query!
Country [289]
0
0
Turkey
Query!
State/province [289]
0
0
Izmir
Query!
Country [290]
0
0
Turkey
Query!
State/province [290]
0
0
Karaman
Query!
Country [291]
0
0
Turkey
Query!
State/province [291]
0
0
Kayseri
Query!
Country [292]
0
0
Turkey
Query!
State/province [292]
0
0
Samsun
Query!
Country [293]
0
0
United Arab Emirates
Query!
State/province [293]
0
0
Abu Dhabi
Query!
Country [294]
0
0
United Arab Emirates
Query!
State/province [294]
0
0
Dubai
Query!
Funding & Sponsors
Primary sponsor type
Commercial sector/industry
Query!
Name
AstraZeneca
Query!
Address
Query!
Country
Query!
Ethics approval
Ethics application status
Query!
Summary
Brief summary
DISCOVER is a Non Interventional Study study to describe the disease management patterns and clinical evolution over three years in type 2 diabetes mellitus patients initiating a second line anti-diabetic treatment.
Query!
Trial website
https://clinicaltrials.gov/study/NCT02322762
Query!
Trial related presentations / publications
Al-Rubeaan K, Banah F, Alruwaily FG, Sheshah E, Alnaqeb D, AlQahtani AM, Ewais D, Al Juhani N, Hassan AH, Youssef AM. Longitudinal assessment of the quality of life and patterns of antidiabetic medication use in patients with type 2 diabetes, Saudi Arabia perspective, DISCOVER study. Curr Med Res Opin. 2023 Jan;39(1):27-35. doi: 10.1080/03007995.2022.2144052. Epub 2022 Nov 28. Mita T, Katakami N, Takahara M, Kawashima M, Wada F, Akiyama H, Morita N, Kidani Y, Yajima T, Shimomura I, Watada H. Changes in Treatment Satisfaction Over 3 Years in Patients With Type 2 Diabetes After Initiating Second-line Treatment. J Clin Endocrinol Metab. 2022 Aug 18;107(9):2424-2432. doi: 10.1210/clinem/dgac420. Hejjaji V, Gorgojo-Martinez JJ, Tang F, Garnelo JB, Cooper A, Medina J, Mutiozabal MS, Khunti K, Nicolucci A, Shestakova MV, Ji L, Gomes MB, Watada H, Vora J, Malik AO, Kosiborod M, Arnold SV. Factors associated with weight loss in people with overweight or obesity living with type 2 diabetes mellitus: Insights from the global DISCOVER study. Diabetes Obes Metab. 2022 Sep;24(9):1734-1740. doi: 10.1111/dom.14745. Epub 2022 May 25. Khunti K, Gomes MB, Kosiborod M, Nicolucci A, Pocock S, Rathmann W, Shestakova MV, Shimomura I, Watada H, Chen H, Cid-Ruzafa J, Fenici P, Hammar N, Tang F, Ji L; DISCOVER Scientific Committee and all DISCOVER investigators. Metformin discontinuation in patients beginning second-line glucose-lowering therapy: results from the global observational DISCOVER study programme. BMJ Open. 2020 Aug 30;10(8):e034613. doi: 10.1136/bmjopen-2019-034613. Wang JS, Chen H, Tang F, Sheu WH. Associations of fear of hypoglycemia with second-line use of insulin secretagogues or insulin and subsequent glycemic control in patients with type 2 diabetes: An analysis using data from the DISCOVER study. Int J Clin Pract. 2020 Jun;74(6):e13485. doi: 10.1111/ijcp.13485. Epub 2020 Feb 11. Khunti K, Chen H, Cid-Ruzafa J, Fenici P, Gomes MB, Hammar N, Ji L, Kosiborod M, Pocock S, Shestakova MV, Shimomura I, Tang F, Watada H, Nicolucci A; DISCOVER investigators. Glycaemic control in patients with type 2 diabetes initiating second-line therapy: Results from the global DISCOVER study programme. Diabetes Obes Metab. 2020 Jan;22(1):66-78. doi: 10.1111/dom.13866. Epub 2019 Oct 1. Nicolucci A, Charbonnel B, Gomes MB, Khunti K, Kosiborod M, Shestakova MV, Shimomura I, Watada H, Chen H, Cid-Ruzafa J, Fenici P, Hammar N, Surmont F, Tang F, Pocock S. Treatment patterns and associated factors in 14 668 people with type 2 diabetes initiating a second-line therapy: Results from the global DISCOVER study programme. Diabetes Obes Metab. 2019 Nov;21(11):2474-2485. doi: 10.1111/dom.13830. Epub 2019 Aug 5. Khunti K, Ji L, Medina J, Surmont F, Kosiborod M. Type 2 diabetes treatment and outcomes worldwide: A short review of the DISCOVER study programme. Diabetes Obes Metab. 2019 Nov;21(11):2349-2353. doi: 10.1111/dom.13817. Epub 2019 Jul 14. Kosiborod M, Gomes MB, Nicolucci A, Pocock S, Rathmann W, Shestakova MV, Watada H, Shimomura I, Chen H, Cid-Ruzafa J, Fenici P, Hammar N, Surmont F, Tang F, Khunti K; DISCOVER investigators. Vascular complications in patients with type 2 diabetes: prevalence and associated factors in 38 countries (the DISCOVER study program). Cardiovasc Diabetol. 2018 Nov 28;17(1):150. doi: 10.1186/s12933-018-0787-8.
Query!
Public notes
Query!
Contacts
Principal investigator
Name
0
0
Jesus Medina, PhD
Query!
Address
0
0
AstraZeneca
Query!
Country
0
0
Query!
Phone
0
0
Query!
Fax
0
0
Query!
Email
0
0
Query!
Contact person for public queries
Name
0
0
Query!
Address
0
0
Query!
Country
0
0
Query!
Phone
0
0
Query!
Fax
0
0
Query!
Email
0
0
Query!
Contact person for scientific queries
No information has been provided regarding IPD availability
What supporting documents are/will be available?
No Supporting Document Provided
Results publications and other study-related documents
No documents have been uploaded by study researchers.
Results not provided in
https://clinicaltrials.gov/study/NCT02322762
Download to PDF