Trial Review

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been endorsed by the ANZCTR. Before participating in a study, talk to your health care provider and refer to this information for consumers
Trial details imported from ClinicalTrials.gov

For full trial details, please see the original record at https://clinicaltrials.gov/ct2/show/NCT02511106




Registration number
NCT02511106
Ethics application status
Date submitted
28/07/2015
Date registered
29/07/2015
Date last updated
27/07/2023

Titles & IDs
Public title
AZD9291 Versus Placebo in Patients With Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy.
Scientific title
A Phase III, Double-blind, Randomized, Placebo-controlled Multi-centre, Study to Assess the Efficacy and Safety of AZD9291 Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mutation Positive Stage IB-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy (ADAURA).
Secondary ID [1] 0 0
2015-000662-65
Secondary ID [2] 0 0
D5164C00001
Universal Trial Number (UTN)
Trial acronym
ADAURA
Linked study record

Health condition
Health condition(s) or problem(s) studied:
Stage IB-IIIA Non-small Cell Lung Carcinoma 0 0
Condition category
Condition code
Cancer 0 0 0 0
Non melanoma skin cancer
Cancer 0 0 0 0
Kidney
Cancer 0 0 0 0
Lung - Mesothelioma
Cancer 0 0 0 0
Lung - Non small cell
Cancer 0 0 0 0
Lung - Small cell

Intervention/exposure
Study type
Interventional
Description of intervention(s) / exposure
Treatment: Drugs - AZD9291 80 mg/40 mg
Treatment: Drugs - Placebo AZD9291 80 mg/40 mg
Treatment: Drugs - Open-label AZD9291 80 mg/40 mg

Experimental: AZD9291 - AZD9291 (80 mg or 40 mg orally, once daily), in accordance with the randomization schedule.

Placebo Comparator: Placebo AZD9291 - Matching placebo for AZD9291 (80 mg or 40 mg orally, once daily), in accordance with the randomization schedule.


Treatment: Drugs: AZD9291 80 mg/40 mg
The initial dose of AZD9291 80 mg once daily can be reduced to 40 mg once daily.

Treatment: Drugs: Placebo AZD9291 80 mg/40 mg
The initial dose of Placebo AZD9291 80 mg once daily can be reduced to 40 mg once daily.

Treatment: Drugs: Open-label AZD9291 80 mg/40 mg
Eligible patients will be offered open-label osimertinib upon recurrence and in the absence of intervening systemic anti-cancer therapy.
Intervention code [1] 0 0
Treatment: Drugs
Comparator / control treatment
Control group

Outcomes
Primary outcome [1] 0 0
Assess the Efficacy of AZD9291 Compared to Placebo as Measured by Disease Free Survival (DFS).
Timepoint [1] 0 0
From date of randomization until date of disease recurrence or death (by any cause in the absence of recurrence), up to approximately 4 years.
Secondary outcome [1] 0 0
Disease Free Survival (DFS) Rate at 2, 3 and 5 Years
Timepoint [1] 0 0
From date of randomization until date of disease recurrence or death (by any cause in the absence of recurrence), up to approximately 4 years. Assessed at 2 years and 3 years.
Secondary outcome [2] 0 0
Overall Survival (OS)
Timepoint [2] 0 0
From date of randomization until date of death due to any cause, up to approximately 4 years.
Secondary outcome [3] 0 0
Overall Survival (OS)
Timepoint [3] 0 0
From date of randomization until date of death due to any cause, up to approximately 4 years.
Secondary outcome [4] 0 0
Overall Survival Rate at 2, 3 and 5 Years
Timepoint [4] 0 0
From date of randomization until date of death due to any cause, up to approximately 4 years. Assessed at 2 years and 3 years.
Secondary outcome [5] 0 0
Patient Health-related Quality of Life and Symptoms (HRQoL) by SF-36v2 Health Survey.
Timepoint [5] 0 0
Measured by SF-36 Questionnaire at baseline, 12 week, 24 week and then every 24 weeks until study complete, disease recurrence or other discontinuation criteria met, up to approximately 3 years.
Secondary outcome [6] 0 0
Plasma Concentrations of AZD9291
Timepoint [6] 0 0
Collected at pre-dose, 0.5-1.5hours and 2-4hours post-dose up to 96 weeks (approximately 24 months)
Secondary outcome [7] 0 0
Plasma Concentrations of AZ5104 Metabolites
Timepoint [7] 0 0
From date of dosing to week 96 (approximately 24 months)
Secondary outcome [8] 0 0
Plasma Concentrations of AZ7550 Metabolites
Timepoint [8] 0 0
From date of dosing to week 96 (approximately 24 months)

Eligibility
Key inclusion criteria
1. Male or female, aged at least 18 years.

2. Histologically confirmed diagnosis of primary non small lung cancer (NSCLC) on
predominantly non-squamous histology

3. MRI or CT scan of the brain must be done prior to surgery as it is considered standard
of care.

4. Patients must be classified post-operatively as Stage IB, II or IIIA on the basis of
pathologic criteria.

5. Confirmation by the central laboratory that the tumour harbours one of the 2 common
EGFR mutations known to be associated with EGFR-TKI sensitivity (Ex19del, L858R),
either alone or in combination with other EGFR mutations including T790M.

6. Complete surgical resection of the primary NSCLC is mandatory. All gross disease must
have been removed at the end of surgery. All surgical margins of resection must be
negative for tumour.

7. Complete recovery from surgery and standard post-operative therapy (if applicable) at
the time of randomization.

8. World Health Organization Performance Status of 0 to 1.

9. Female patients should be using adequate contraceptive measures, should not be breast
feeding, and must have a negative pregnancy test prior to first dose of study drug; or
female patients must have an evidence of non-child-bearing potential.
Minimum age
18 Years
Maximum age
130 Years
Sex
Both males and females
Can healthy volunteers participate?
No
Key exclusion criteria
1. Treatment with any of the following:

- Pre-operative or post-operative or planned radiation therapy for the current lung
cancer

- Pre-operative (neo-adjuvant) platinum based or other chemotherapy

- Any prior anticancer therapy

- Prior treatment with neoadjuvant or adjuvant EGFR-TKI at any time

- Major surgery (including primary tumour surgery, excluding placement of vascular
access) within 4 weeks of the first dose of study drug

- Patients currently receiving medications or herbal supplements known to be potent
inducers of cytochrome P450 (CYP) 3A4

- Treatment with an investigational drug within five half-lives of the compound or
any of its related material.

2. Patients who have had only segmentectomies or wedge resections

3. History of other malignancies, except: adequately treated non-melanoma skin cancer,
curatively treated in-situ cancer, or other solid tumours curatively treated with no
evidence of disease for > 5 years following the end of treatment.

4. Any unresolved toxicities from prior therapy greater than CTCAE Grade 1 at the time of
starting study treatment with the exception of alopecia and Grade 2, prior
platinum-therapy related neuropathy.

5. Any evidence of severe or uncontrolled systemic diseases, including uncontrolled
hypertension and active bleeding diatheses; or active infection including hepatitis B,
hepatitis C and human immunodeficiency virus (HIV).

6. Refractory nausea and vomiting, chronic gastrointestinal diseases, inability to
swallow the formulated product, or previous significant bowel resection that would
preclude adequate absorption of AZD9291.

7. Any of the following cardiac criteria:

- Mean resting corrected QT interval (QTc) >470 msec, obtained from 3 ECGs, using
the screening clinic ECG machine-derived QTc value.

- Any clinically important abnormalities in rhythm, conduction, or morphology of
resting ECG.

- Any factors that increase the risk of QTc prolongation or risk of arrhythmic
events, or unexplained sudden death under 40 years of age in first-degree
relatives or any concomitant medication known to prolong the QT interval.

8. Past medical history of ILD, drug-induced ILD, radiation pneumonitis which required
steroid treatment, or any evidence of clinically active ILD.

9. Inadequate bone marrow reserve or organ function.

Study design
Purpose of the study
Treatment
Allocation to intervention
Randomised controlled trial
Procedure for enrolling a subject and allocating the treatment (allocation concealment procedures)
Methods used to generate the sequence in which subjects will be randomised (sequence generation)
Masking / blinding
Blinded (masking used)
Who is / are masked / blinded?
The people receiving the treatment/s

The people assessing the outcomes
The people analysing the results/data
Intervention assignment
Parallel
Other design features
Phase
Phase 3
Type of endpoint/s
Statistical methods / analysis

Recruitment
Recruitment status
Active, not recruiting
Data analysis
Reason for early stopping/withdrawal
Other reasons
Date of first participant enrolment
Anticipated
Actual
21/10/2015
Date of last participant enrolment
Anticipated
Actual
Date of last data collection
Anticipated
31/12/2030
Actual
Sample size
Target
Accrual to date
Final
682
Recruitment in Australia
Recruitment state(s)
Recruitment hospital [1] 0 0
Research Site - Bedford Park
Recruitment hospital [2] 0 0
Research Site - Camperdown
Recruitment hospital [3] 0 0
Research Site - Darlinghurst
Recruitment hospital [4] 0 0
Research Site - Heidelberg
Recruitment hospital [5] 0 0
Research Site - Kogarah
Recruitment hospital [6] 0 0
Research Site - Kurralta Park
Recruitment hospital [7] 0 0
Research Site - Woolloongabba
Recruitment postcode(s) [1] 0 0
5042 - Bedford Park
Recruitment postcode(s) [2] 0 0
2050 - Camperdown
Recruitment postcode(s) [3] 0 0
2010 - Darlinghurst
Recruitment postcode(s) [4] 0 0
3084 - Heidelberg
Recruitment postcode(s) [5] 0 0
2217 - Kogarah
Recruitment postcode(s) [6] 0 0
5037 - Kurralta Park
Recruitment postcode(s) [7] 0 0
4102 - Woolloongabba
Recruitment outside Australia
Country [1] 0 0
United States of America
State/province [1] 0 0
California
Country [2] 0 0
United States of America
State/province [2] 0 0
Colorado
Country [3] 0 0
United States of America
State/province [3] 0 0
Connecticut
Country [4] 0 0
United States of America
State/province [4] 0 0
Florida
Country [5] 0 0
United States of America
State/province [5] 0 0
Georgia
Country [6] 0 0
United States of America
State/province [6] 0 0
Hawaii
Country [7] 0 0
United States of America
State/province [7] 0 0
Illinois
Country [8] 0 0
United States of America
State/province [8] 0 0
Maryland
Country [9] 0 0
United States of America
State/province [9] 0 0
New Jersey
Country [10] 0 0
United States of America
State/province [10] 0 0
New York
Country [11] 0 0
United States of America
State/province [11] 0 0
Rhode Island
Country [12] 0 0
United States of America
State/province [12] 0 0
Tennessee
Country [13] 0 0
United States of America
State/province [13] 0 0
Texas
Country [14] 0 0
United States of America
State/province [14] 0 0
Virginia
Country [15] 0 0
Belgium
State/province [15] 0 0
Brussels
Country [16] 0 0
Belgium
State/province [16] 0 0
Brussel
Country [17] 0 0
Belgium
State/province [17] 0 0
Gent
Country [18] 0 0
Belgium
State/province [18] 0 0
Kortrijk
Country [19] 0 0
Brazil
State/province [19] 0 0
Barretos
Country [20] 0 0
Brazil
State/province [20] 0 0
Cachoeira De Itapemirim
Country [21] 0 0
Brazil
State/province [21] 0 0
Curitiba
Country [22] 0 0
Brazil
State/province [22] 0 0
Florianópolis
Country [23] 0 0
Brazil
State/province [23] 0 0
Fortaleza
Country [24] 0 0
Brazil
State/province [24] 0 0
Lajeado
Country [25] 0 0
Brazil
State/province [25] 0 0
Porto Alegre
Country [26] 0 0
Brazil
State/province [26] 0 0
Rio de Janeiro
Country [27] 0 0
Brazil
State/province [27] 0 0
Salvador
Country [28] 0 0
Brazil
State/province [28] 0 0
São José do Rio Preto
Country [29] 0 0
Brazil
State/province [29] 0 0
São Paulo
Country [30] 0 0
Canada
State/province [30] 0 0
Ontario
Country [31] 0 0
China
State/province [31] 0 0
Beijing
Country [32] 0 0
China
State/province [32] 0 0
Changchun
Country [33] 0 0
China
State/province [33] 0 0
Dalian
Country [34] 0 0
China
State/province [34] 0 0
Guangzhou
Country [35] 0 0
China
State/province [35] 0 0
Hangzhou
Country [36] 0 0
China
State/province [36] 0 0
Kunming
Country [37] 0 0
China
State/province [37] 0 0
Nanjing
Country [38] 0 0
China
State/province [38] 0 0
Nanning
Country [39] 0 0
China
State/province [39] 0 0
Shanghai
Country [40] 0 0
China
State/province [40] 0 0
Shenyang
Country [41] 0 0
China
State/province [41] 0 0
Suzhou
Country [42] 0 0
China
State/province [42] 0 0
Tianjin
Country [43] 0 0
China
State/province [43] 0 0
Urumqi
Country [44] 0 0
China
State/province [44] 0 0
Xi'an
Country [45] 0 0
China
State/province [45] 0 0
Xiamen
Country [46] 0 0
China
State/province [46] 0 0
Yangzhou
Country [47] 0 0
China
State/province [47] 0 0
Zhengzhou
Country [48] 0 0
China
State/province [48] 0 0
Ürümqi
Country [49] 0 0
France
State/province [49] 0 0
Bron
Country [50] 0 0
France
State/province [50] 0 0
Lille
Country [51] 0 0
France
State/province [51] 0 0
Limoges Cedex
Country [52] 0 0
France
State/province [52] 0 0
Lyon
Country [53] 0 0
France
State/province [53] 0 0
Paris
Country [54] 0 0
Germany
State/province [54] 0 0
Aachen
Country [55] 0 0
Germany
State/province [55] 0 0
Berlin
Country [56] 0 0
Germany
State/province [56] 0 0
Coswig
Country [57] 0 0
Germany
State/province [57] 0 0
Gauting
Country [58] 0 0
Germany
State/province [58] 0 0
Gerlingen
Country [59] 0 0
Germany
State/province [59] 0 0
Großhansdorf
Country [60] 0 0
Germany
State/province [60] 0 0
Halle
Country [61] 0 0
Germany
State/province [61] 0 0
Hamburg
Country [62] 0 0
Germany
State/province [62] 0 0
Homburg
Country [63] 0 0
Germany
State/province [63] 0 0
Immenhausen
Country [64] 0 0
Germany
State/province [64] 0 0
Kassel
Country [65] 0 0
Germany
State/province [65] 0 0
Köln
Country [66] 0 0
Germany
State/province [66] 0 0
Lübeck
Country [67] 0 0
Germany
State/province [67] 0 0
Würzburg
Country [68] 0 0
Hong Kong
State/province [68] 0 0
Hong Kong
Country [69] 0 0
Hong Kong
State/province [69] 0 0
King's Park
Country [70] 0 0
Hungary
State/province [70] 0 0
Budapest
Country [71] 0 0
Hungary
State/province [71] 0 0
Deszk
Country [72] 0 0
Hungary
State/province [72] 0 0
Székesfehérvár
Country [73] 0 0
Hungary
State/province [73] 0 0
Törökbálint
Country [74] 0 0
Israel
State/province [74] 0 0
Beer-Sheva
Country [75] 0 0
Israel
State/province [75] 0 0
Haifa
Country [76] 0 0
Israel
State/province [76] 0 0
Jerusalem
Country [77] 0 0
Israel
State/province [77] 0 0
Kfar-Saba
Country [78] 0 0
Israel
State/province [78] 0 0
Petah Tikva
Country [79] 0 0
Israel
State/province [79] 0 0
Ramat Gan
Country [80] 0 0
Israel
State/province [80] 0 0
Tel Aviv
Country [81] 0 0
Italy
State/province [81] 0 0
Bari
Country [82] 0 0
Italy
State/province [82] 0 0
Bergamo
Country [83] 0 0
Italy
State/province [83] 0 0
Bologna
Country [84] 0 0
Italy
State/province [84] 0 0
Cremona
Country [85] 0 0
Italy
State/province [85] 0 0
Firenze
Country [86] 0 0
Italy
State/province [86] 0 0
Lucca
Country [87] 0 0
Italy
State/province [87] 0 0
Meldola
Country [88] 0 0
Italy
State/province [88] 0 0
Milano
Country [89] 0 0
Italy
State/province [89] 0 0
Novara
Country [90] 0 0
Italy
State/province [90] 0 0
Orbassano
Country [91] 0 0
Italy
State/province [91] 0 0
Padova
Country [92] 0 0
Italy
State/province [92] 0 0
Parma
Country [93] 0 0
Italy
State/province [93] 0 0
Roma
Country [94] 0 0
Japan
State/province [94] 0 0
Bunkyo-ku
Country [95] 0 0
Japan
State/province [95] 0 0
Fukuoka
Country [96] 0 0
Japan
State/province [96] 0 0
Hirakata-shi
Country [97] 0 0
Japan
State/province [97] 0 0
Hiroshima-shi
Country [98] 0 0
Japan
State/province [98] 0 0
Kanazawa
Country [99] 0 0
Japan
State/province [99] 0 0
Kashiwa
Country [100] 0 0
Japan
State/province [100] 0 0
Kitakyushu-shi
Country [101] 0 0
Japan
State/province [101] 0 0
Kobe-shi
Country [102] 0 0
Japan
State/province [102] 0 0
Kurume-shi
Country [103] 0 0
Japan
State/province [103] 0 0
Matsuyama-shi
Country [104] 0 0
Japan
State/province [104] 0 0
Nagoya-shi
Country [105] 0 0
Japan
State/province [105] 0 0
Niigata-shi
Country [106] 0 0
Japan
State/province [106] 0 0
Osakasayama-shi
Country [107] 0 0
Japan
State/province [107] 0 0
Sagamihara-shi
Country [108] 0 0
Japan
State/province [108] 0 0
Sakai-shi
Country [109] 0 0
Japan
State/province [109] 0 0
Sasebo-shi
Country [110] 0 0
Japan
State/province [110] 0 0
Sendai-shi
Country [111] 0 0
Japan
State/province [111] 0 0
Shinjuku-ku
Country [112] 0 0
Japan
State/province [112] 0 0
Sunto-gun
Country [113] 0 0
Japan
State/province [113] 0 0
Ube-shi
Country [114] 0 0
Japan
State/province [114] 0 0
Yokohama-shi
Country [115] 0 0
Japan
State/province [115] 0 0
Yonago-shi
Country [116] 0 0
Korea, Republic of
State/province [116] 0 0
Cheongju-si
Country [117] 0 0
Korea, Republic of
State/province [117] 0 0
Seoul
Country [118] 0 0
Korea, Republic of
State/province [118] 0 0
Suwon
Country [119] 0 0
Netherlands
State/province [119] 0 0
Amsterdam
Country [120] 0 0
Netherlands
State/province [120] 0 0
Arnhem
Country [121] 0 0
Netherlands
State/province [121] 0 0
Hoofddorp
Country [122] 0 0
Netherlands
State/province [122] 0 0
Zwolle
Country [123] 0 0
Poland
State/province [123] 0 0
Kraków
Country [124] 0 0
Poland
State/province [124] 0 0
Otwock
Country [125] 0 0
Poland
State/province [125] 0 0
Poznan
Country [126] 0 0
Poland
State/province [126] 0 0
Racibórz
Country [127] 0 0
Poland
State/province [127] 0 0
Warszawa
Country [128] 0 0
Poland
State/province [128] 0 0
Wieliszew
Country [129] 0 0
Poland
State/province [129] 0 0
Lódz
Country [130] 0 0
Romania
State/province [130] 0 0
Bucharest
Country [131] 0 0
Romania
State/province [131] 0 0
Bucuresti
Country [132] 0 0
Romania
State/province [132] 0 0
Cluj Napoca
Country [133] 0 0
Romania
State/province [133] 0 0
Craiova
Country [134] 0 0
Romania
State/province [134] 0 0
Focsani
Country [135] 0 0
Romania
State/province [135] 0 0
Iasi
Country [136] 0 0
Romania
State/province [136] 0 0
Timisoara
Country [137] 0 0
Russian Federation
State/province [137] 0 0
Arkhangelsk
Country [138] 0 0
Russian Federation
State/province [138] 0 0
Kazan
Country [139] 0 0
Russian Federation
State/province [139] 0 0
Moscow
Country [140] 0 0
Russian Federation
State/province [140] 0 0
Obninsk
Country [141] 0 0
Russian Federation
State/province [141] 0 0
Omsk
Country [142] 0 0
Russian Federation
State/province [142] 0 0
Pyatigorsk
Country [143] 0 0
Russian Federation
State/province [143] 0 0
Rostov-on-Don
Country [144] 0 0
Russian Federation
State/province [144] 0 0
Ryazan
Country [145] 0 0
Russian Federation
State/province [145] 0 0
Saint Petersburg
Country [146] 0 0
Russian Federation
State/province [146] 0 0
Saint-Petersburg
Country [147] 0 0
Russian Federation
State/province [147] 0 0
Sankt-Peterburg
Country [148] 0 0
Russian Federation
State/province [148] 0 0
St. Petersburg
Country [149] 0 0
Spain
State/province [149] 0 0
A Coruña
Country [150] 0 0
Spain
State/province [150] 0 0
Barcelona
Country [151] 0 0
Spain
State/province [151] 0 0
Elche
Country [152] 0 0
Spain
State/province [152] 0 0
Las Palmas de Gran Canaria
Country [153] 0 0
Spain
State/province [153] 0 0
Madrid
Country [154] 0 0
Spain
State/province [154] 0 0
Majadahonda
Country [155] 0 0
Spain
State/province [155] 0 0
Málaga
Country [156] 0 0
Spain
State/province [156] 0 0
San Sebastian
Country [157] 0 0
Spain
State/province [157] 0 0
Valencia
Country [158] 0 0
Spain
State/province [158] 0 0
Zaragoza
Country [159] 0 0
Sweden
State/province [159] 0 0
Linköping
Country [160] 0 0
Taiwan
State/province [160] 0 0
Changhua
Country [161] 0 0
Taiwan
State/province [161] 0 0
Putzu City
Country [162] 0 0
Taiwan
State/province [162] 0 0
Taichung City
Country [163] 0 0
Taiwan
State/province [163] 0 0
Taichung
Country [164] 0 0
Taiwan
State/province [164] 0 0
Tainan City
Country [165] 0 0
Taiwan
State/province [165] 0 0
Tainan
Country [166] 0 0
Taiwan
State/province [166] 0 0
Taipei
Country [167] 0 0
Taiwan
State/province [167] 0 0
Tao-Yuan
Country [168] 0 0
Thailand
State/province [168] 0 0
Bangkok
Country [169] 0 0
Thailand
State/province [169] 0 0
Chiang Rai
Country [170] 0 0
Thailand
State/province [170] 0 0
Khon Kaen
Country [171] 0 0
Thailand
State/province [171] 0 0
Mueang
Country [172] 0 0
Thailand
State/province [172] 0 0
Phitsanulok
Country [173] 0 0
Thailand
State/province [173] 0 0
Songkla
Country [174] 0 0
Turkey
State/province [174] 0 0
Ankara
Country [175] 0 0
Turkey
State/province [175] 0 0
Bursa
Country [176] 0 0
Turkey
State/province [176] 0 0
Istanbul
Country [177] 0 0
Turkey
State/province [177] 0 0
Izmir
Country [178] 0 0
Ukraine
State/province [178] 0 0
Dnipro
Country [179] 0 0
Ukraine
State/province [179] 0 0
Lviv
Country [180] 0 0
Ukraine
State/province [180] 0 0
Sumy
Country [181] 0 0
Ukraine
State/province [181] 0 0
Uzhhorod
Country [182] 0 0
Ukraine
State/province [182] 0 0
Vinnytsia
Country [183] 0 0
Ukraine
State/province [183] 0 0
Zaporizhzhia
Country [184] 0 0
Vietnam
State/province [184] 0 0
Hanoi
Country [185] 0 0
Vietnam
State/province [185] 0 0
Ho Chi Minh

Funding & Sponsors
Primary sponsor type
Commercial sector/Industry
Name
AstraZeneca
Address
Country

Ethics approval
Ethics application status

Summary
Brief summary
To assess the efficacy and safety of AZD9291 versus Placebo, in patients with Epidermal
Growth Factor Receptor Mutation Positive stage IB-IIIA non-small cell lung carcinoma,
following complete tumour resection with or without adjuvant chemotherapy
Trial website
https://clinicaltrials.gov/ct2/show/NCT02511106
Trial related presentations / publications
Public notes

Contacts
Principal investigator
Name 0 0
Address 0 0
Country 0 0
Phone 0 0
Fax 0 0
Email 0 0
Contact person for public queries
Name 0 0
Address 0 0
Country 0 0
Phone 0 0
Fax 0 0
Email 0 0
Contact person for scientific queries



Summary Results

For IPD and results data, please see https://clinicaltrials.gov/ct2/show/NCT02511106